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Prohibitins control cell proliferation and apoptosis by regulating OPA1-dependent Cristae morphogenesis in mitochondria

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J Invest Dermatol (2022) 142(2):44558

For example, after systemic administration of GH for 14 days, human data have reported an increase in circulating IGF-1 and expression of IGF-1 in tendon tissue, accompanied by increased expression of tendon collagen in individuals ( in vivo studies, which have demonstrated that local administration of IGF-1 (1 mg) directly induced an elevation in collagen synthesis in human tendon tissue ( The above findings combined to demonstrate that IGF-1 is sufficient to increase collagen production in tenocytes

Modulation of TGF- signaling new approaches toward kidney disease and fibrosis therapy